Poisonous Intent - Batman: Arkham City (2011)

Ready to turn over a new leaf, Pamela Isley rejected her Poison Ivy persona and opened a small flower shop in the backstreets of Gotham. Surrounded plants, she was content for a while. But society continued to mistreat her "babies" and eventually, she snapped.

A man came to buy flowers for his wife, obviously feeling guilty about having been unfaithful. Pamela smiled and handed over an elaborate bouquet. The plants came to life, rapidly growing onto his screaming face and piercing his skin with toxic thorns. Pamela laughed. Poison Ivy was back.

After being given an overdose of TITAN by the Joker, Poison Ivy was left to die in her airtight cell by Warden Sharp, who blamed her for the mass destruction of Arkham Island.

As her health declined, she prayed for salvation. It came in the form of a priest, who was unknowingly covered in pollen from the trees near his church. As he performed the last rites, Ivy manipulated the pollen into an antidote that worked in harmony with the unique, natural toxins in her blood, and to the amazement of the priest, she began a full recovery.

Furious, Warden Sharp locked her in a biological containment unit and arranged for her to be one of the first criminals sent to Arkham City.